AIFM1 Mouse Monoclonal Antibody
产品名称： AIFM1 Mouse Monoclonal Antibody
英文名称： AIFM1 Mouse Monoclonal Antibody
产品编号： K000163M
产品价格： null
产品产地： 北京市通州区马驹桥
品牌商标： solarbio
更新时间： 2025-11-13T16:50:54
使用范围： WB IF
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
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Anti-AIFM1 Monoclonal Antibody
品牌：solarbio | 货号：K000163M
| 宿主 | Mouse |
|---|---|
| 英文名称 | Anti-AIFM1 Monoclonal Antibody |
| 别名 | AIF;CMT2D;CMTX4;COWCK;COXPD6;DFNX5;NADMR;NAMSD;PDCD8 |
| 应用 | WB IF |
| 稀释比例 | WB 1:1000. ICC 1:200. |
| 交叉反应 | Human |
| 蛋白分子量 | 67kDa |
| Gene ID | 9131 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG2a |
| 免疫原 | Purified recombinant human AIFM1 protein fragments expressed in E.coli. |
| 性状 | 液体 |
| Subcellular Locations | Cytoplasm Mitochondrion inner membrane Mitochondrion intermembrane space Nucleus perinuclear region |
| Swiss Prot | O95831 |
| 克隆号 | 8H1-B10-A12 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. |