PPP5C (C-term) Peptide
产品名称: PPP5C (C-term) Peptide
英文名称: PPP5C (C-term) Peptide
产品编号: P3330
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
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 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Rabbit polyclonal antibody raised against synthetic peptide of PPP5C.
 
- Immunogen:
 - A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PPP5C.
 
- Host:
 - Rabbit
 
- Reactivity:
 - Human
 
- Form:
 - Liquid
 
- Purification:
 - Protein G purification
 
- Storage Buffer:
 - In PBS (0.09% sodium azide)
 
- Storage Instruction:
 - Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. 
- Recommend Usage:
 - ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user. 
- Note:
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 
- Publication Reference
 
- 1.
 - Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.
Yang J, Roe SM, Cliff MJ, Williams MA, Ladbury JE, Cohen PT, Barford D.EMBO J. 2005 Jan 12;24(1):1-10. Epub 2004 Dec 2. 
- 2.
 - Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade.
Zhou G, Golden T, Aragon IV, Honkanen RE.J Biol Chem. 2004 Nov 5;279(45):46595-605. Epub 2004 Aug 24. 
- 3.
 - Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.
Huang S, Shu L, Easton J, Harwood FC, Germain GS, Ichijo H, Houghton PJ.J Biol Chem. 2004 Aug 27;279(35):36490-6. Epub 2004 Jun 24. 
- Applications
 
- Western Blot (Cell lysate)
 
- The PPP5C polyclonal antibody (Cat # PAB4172) is used in Western blot to detect PPP5C in HL-60 cell lysate.
 
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
 
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PPP5C polyclonal antibody (Cat # PAB4172) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 
- Gene Pathway
 
